Because quality matters – B·R·A·H·M·S PCT assays

Are you using a quality PCT assay? Look closer!

BRAHMS-PCT-quality

There are Procalcitonin assays in the market that claim to use the same standards as B·R·A·H·M·S PCT but they are not: Neither do these assays make use of the validated B·R·A·H·M·S antibodies nor do they belong to the licensed B·R·A·H·M·S PCT assays with standardized quality and proven evidence. Only assays specifying "B·R·A·H·M·S PCT" in their product name are based on B·R·A·H·M·S antibodies and can refer to established clinical PCT cut-offs (see table below).

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Better trust the original – B·R·A·H·M·S PCT

B·R·A·H·M·S PCT assays have been demonstrated to
improve the accuracy of diagnosis and risk assessment in bacterial infection and sepsis¹ and to guide antibiotic therapy-related decisions². PCT cut-offs and clinical algorithms were established by use of B·R·A·H·M·S PCT sensitive KRYPTOR assay which is the global reference standard

For safe use of these cut-offs and algorithms with other PCT assays it is important to verify that these assays will provide the same result
The most important criteria for the comparative performance are:
- High correlation to reference
- High assay sensitivity and precision
- High concordance at clinically relevant cut-offs

All B·R·A·H·M·S PCT assays use original raw material from B·R·A·H·M·S GmbH, are calibrated on the same standard and offer excellent correlation and concordance at the established clinical cut-offs.

B·R·A·H·M·S PCT - Secured clinical decision making independent of the platform

	B·R·A·H·M·S PCT sensitive KRYPTOR B·R·A·H·M·S PCT direct B·R·A·H·M·S PCT-Q B·R·A·H·M·S PCT LIA		CE marked / FDA 510(k) cleared
			CE marked
			CE marked
			CE marked / FDA 510(k) cleared
	ALINITY i B·R·A·H·M·S PCT ARCHITECT B·R·A·H·M·S PCT		CE marked / FDA 510(k) cleared. CE marked / FDA 510(k) cleared
	VIDAS B·R·A·H·M·S PCT		CE marked / FDA 510(k) cleared
	LIAISON B·R·A·H·M·S PCT		CE marked / FDA 510(k) cleared
	Lumipulse B·R·A·H·M·S PCT		CE marked / FDA 510(k) cleared
	ELECSYS B·R·A·H·M·S PCT		CE marked / FDA 510(k) cleared
	Samsung IB B·R·A·H·M·S PCT		CE marked
	ADVIA Centaur B·R·A·H·M·S PCT ATELLICA IM B·R·A·H·M·S PCT		CE marked CE marked / FDA 510(k) cleared

Automated sensitive assay

Point of care test

Manual assay

1. Soni N.J. et al., J Hosp Med 2013;8 (9): 530-40.
2. Meisner, M., Procalcitonin – Biochemistry and Clinical Diagnosis, UNI-MED (Bremen) 2010; ISBN 978-3-8374-1241-3.