Are you using a quality PCT assay? Look closer!
There are Procalcitonin assays in the market that claim to use the same standards as B·R·A·H·M·S PCT but they are not: Neither do these assays make use of the validated B·R·A·H·M·S antibodies nor do they belong to the licensed B·R·A·H·M·S PCT assays with standardized quality and proven evidence. Only assays specifying "B·R·A·H·M·S PCT" in their product name are based on B·R·A·H·M·S antibodies and can refer to established clinical PCT cut-offs (see table below).
Better trust the original – B·R·A·H·M·S PCT
B·R·A·H·M·S PCT assays have been demonstrated toimprove the accuracy of diagnosis and risk assessment in bacterial infection and sepsis1 and to guide antibiotic therapy-related decisions2. PCT cut-offs and clinical algorithms were established by use of B·R·A·H·M·S PCT sensitive KRYPTOR assay which is the global reference standard
- For safe use of these cut-offs and algorithms with other PCT assays it is important to verify that these assays will provide the same result
- The most important criteria for the comparative performance are:
- High correlation to reference
- High assay sensitivity and precision
- High concordance at clinically relevant cut-offs
All B·R·A·H·M·S PCT assays use original raw material from B·R·A·H·M·S GmbH, are calibrated on the same standard and offer excellent correlation and concordance at the established clinical cut-offs.
B·R·A·H·M·S PCT - Secured clinical decision making independent of the platform
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B·R·A·H·M·S PCT sensitive KRYPTOR |
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CE marked / FDA 510(k) cleared |
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CE marked | ||
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CE marked | ||
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CE marked / FDA 510(k) cleared | ||
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CE marked / FDA 510(k) cleared. |
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VIDAS B·R·A·H·M·S PCT | ![]() |
CE marked / FDA 510(k) cleared |
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LIAISON B·R·A·H·M·S PCT | ![]() |
CE marked / FDA 510(k) cleared |
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Lumipulse B·R·A·H·M·S PCT | ![]() |
CE marked / FDA 510(k) cleared |
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VITROS B·R·A·H·M·S PCT | ![]() |
CE marked / FDA 510(k) cleared |
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ELECSYS B·R·A·H·M·S PCT | ![]() |
CE marked / FDA 510(k) cleared |
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ADVIA Centaur B·R·A·H·M·S PCT ATELLICA IM B·R·A·H·M·S PCT |
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CE marked |
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1. Soni N.J. et al., J Hosp Med 2013;8 (9): 530-40.
2. Meisner, M., Procalcitonin – Biochemistry and Clinical Diagnosis, UNI-MED (Bremen) 2010; ISBN 978-3-8374-1241-3.