Definitions for the terms of "SIRS - Systemic Inflammatory Response Syndrome", "sepsis", "severe sepsis" or "septic shock" have been proposed by the ACCP/SCCM Consensus Conference in 1992, and are now widely used.
New sepsis concept under development (PIRO)
This model integrates a number of currently available parameters, which describe the Predisposition, the Infection, the Response and the Organ dysfunction. PCT has been proposed as one of the the most valuable parameters to be included into this assessment scheme.
(2001 SCCM/ESICM/ACCP/ATS/SIS International Sepsis Definitions Conference, Levy MM et al., Crit. Care Med. 2003, 31(4): 1250-1256)